HPTN 052 – Site PI: Prof. Johnstone Kumwenda
Randomized Trial to Evaluate the Effectiveness of Antiretroviral Therapy Plus HIV Primary Care versus HIV Primary Care Alone to Prevent the Sexual Transmission of HIV-1 in Serodiscordant Couples.
HPTN 084 – Site PI: Dr. Noel Kayange
A Phase 3 Double Blind Safety and Efficacy Study of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women.
HVTN 703 / HPTN 081 – Site PI: Prof. Johnstone Kumwenda
A phase 2b study to evaluate the safety and efficacy of VRC01 broadly neutralizing monoclonal antibody in reducing acquisition of HIV-1 infection in women in sub-Saharan Africa.
HPTN 035 – Site PI: Late Prof. Bonus Makanani
Phase II/IIb, four-arm, multisite, randomized controlled trial to evaluate the safety and effectiveness of two candidate vaginal microbicides, BufferGel and 0.5% PRO 2000/5 Gel (P), for the prevention of HIV infection in women.
IMPAACT 1077 – Site PI: Late Prof. Bonus Makanani & Dr. Luis Gadama
PROMISE Study – Promoting Maternal and Infant Survival Everywhere
CoVPN 3008 – Site PI: Dr. Noel Kayange
Efficacy Study of COVID-19 mRNA Vaccine in Regions with SARS-CoV-2 Variants of Concern (CoVPN3008)
MTN 020 – Site PI: Late Dr. George Kafulafula & Late Prof. Bonus Makanani
The power of the shared experience: MTN-020/ASPIRE trial participants’ descriptions of peer influence on acceptability of and adherence to the dapivirine vaginal ring for HIV prevention
ACTG 5379 – Site PI: Dr. Mulinda Nyirenda
B-Enhancement of HBV vaccinatoin in persons living with HIV (BEe-HIVe): Evaluation of HEPLISAV-B
PALISADE – Site PI: Dr. Noel Kayange
Long-term Follow-up of Long-acting Cabotegravir (CAB LA) for PrEP (Pre-exposure Prophylaxis) in Participants at Risk of Acquiring HIV (Human Immunodeficiency Virus) (PALISADE)
IMPAACT 2009 – Site PI: Dr. Frank Taulo & Dr. Sharon Mambiya
Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for Primary HIV Prevention during Pregnancy and Postpartum in Adolescents and Young Women and their Infants